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Independent directory. VektorIndex is not affiliated with or sponsored by any third-party vendor. (VektorIndex's own developer tools are also listed, identified by name.) All specifications are sourced from official vendor documentation and are not independently audited.
Note: Epic Systems (Healthcare Software) and Salesforce Sales Cloud (CRM) are in different software categories. This comparison may be relevant if you are evaluating them for overlapping use cases. For same-category comparisons, browse Healthcare Software tools.

Head-to-Head Specification Audit

Epic Systems vs Salesforce Sales Cloud

Enterprise Electronic Health Records · United States

Healthcare Software

Epic Systems

Enterprise Electronic Health Records · United States

Visit Epic Systems

CRM

Salesforce Sales Cloud

Enterprise CRM Platform · Global

Visit Salesforce Sales Cloud

Specification Matrix

MetricEpic SystemsSalesforce Sales Cloud
Starting PriceCustom pricing$25/mo
API Rate Limit200 req/min1000 req/minBetter
Target CountryUnited StatesGlobal
CategoryHealthcare SoftwareCRM
Compliance (vendor-stated)HIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMDSOC2, GDPR, HIPAA, ISO27001, CCPA, POPIA
Hosting RegionsUS-East, US-WestUS-East, EU-West, AP-Southeast
Native Integrations5 listed6 listedBetter

Epic Systems — Key Specs

Vendor-stated
  • Largest EHR market share (35%+ of US hospital beds)
  • MyChart patient portal with 200M+ registered patients
  • Epic AI (Cosmos) — largest real-world clinical dataset for AI training
  • ONC-certified, HIPAA, HL7 FHIR R4 compliant

Salesforce Sales Cloud — Key Specs

Vendor-stated
  • Market leader: 20%+ CRM market share
  • Einstein AI: lead scoring, opportunity forecasting, next best action
  • AppExchange: 5,000+ third-party integrations
  • SOC 2 Type II, ISO 27001, GDPR, HIPAA compliant

Frequently Asked Questions

Which is lower-priced, Epic Systems or Salesforce Sales Cloud?+

Epic Systems uses custom pricing. Salesforce Sales Cloud starts at $25/mo. Contact Epic Systems directly for a quote.

Which compliance frameworks do Epic Systems and Salesforce Sales Cloud list?+

Both list HIPAA, SOC2 in their vendor documentation. Epic Systems additionally lists ONC, HL7-FHIR, FDA-SaMD. Salesforce Sales Cloud additionally lists GDPR, ISO27001, CCPA, POPIA. These are vendor-stated frameworks. VektorIndex has not independently audited these claims.

Does Epic Systems or Salesforce Sales Cloud list POPIA as a supported compliance framework?+

Salesforce Sales Cloud lists POPIA (Protection of Personal Information Act) as a supported compliance framework per its vendor documentation. VektorIndex has not independently verified this claim. South African organisations should request the vendor's current Data Processing Agreement and confirm data residency settings before processing personal information. Epic Systems does not list POPIA as a supported compliance framework in its public documentation. Contact the vendor to confirm their position before processing South African personal information.

Which has a higher documented API rate limit — Epic Systems or Salesforce Sales Cloud?+

Salesforce Sales Cloud has a higher documented API rate limit at 1000 req/min versus Epic Systems at 200 req/min.

Which data hosting regions do Epic Systems and Salesforce Sales Cloud support?+

Epic Systems lists hosting regions: US-East, US-West. Salesforce Sales Cloud lists hosting regions: US-East, EU-West, AP-Southeast. For data residency requirements in United States, confirm exact region configuration directly with each vendor.

Data last updated: 29 August 2026Sourced from official vendor documentation. Not independently audited. Report incorrect information

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