Head-to-Head Specification Audit
Epic Systems vs Salesforce
Enterprise Electronic Health Records · United States
Healthcare Software
Epic Systems
Enterprise Electronic Health Records · United States
Visit Epic Systems →Specification Matrix
| Metric | Epic Systems | Salesforce |
|---|---|---|
| Starting Price | Custom pricing | $25/mo |
| API Rate Limit | 200 req/min | 1000 req/minBetter |
| Target Country | United States | Global |
| Category | Healthcare Software | CRM |
| Compliance (vendor-stated) | HIPAA, ONC, SOC2, HL7-FHIR, FDA-SaMD | GDPR, CCPA, POPIA, SOC2, ISO27001, FedRAMP |
| Hosting Regions | US-East, US-West | US-East, EU-West, AP-Southeast, AU-East |
| Native Integrations | 5 listed | 7 listedBetter |
Epic Systems — Key Specs
Vendor-stated- ✓Largest EHR market share (35%+ of US hospital beds)
- ✓MyChart patient portal with 200M+ registered patients
- ✓Epic AI (Cosmos) — largest real-world clinical dataset for AI training
- ✓ONC-certified, HIPAA, HL7 FHIR R4 compliant
Salesforce — Key Specs
Vendor-stated- ✓Einstein AI forecasting surfaces at-risk deals before they slip
- ✓AppExchange has 7,000+ certified B2B integrations
- ✓POPIA and GDPR data governance controls built into Org settings
- ✓Customisable objects and flows handle any sales process complexity
Frequently Asked Questions
Which is lower-priced, Epic Systems or Salesforce?+
Epic Systems uses custom pricing. Salesforce starts at $25/mo. Contact Epic Systems directly for a quote.
Which compliance frameworks do Epic Systems and Salesforce list?+
Both list SOC2 in their vendor documentation. Epic Systems additionally lists HIPAA, ONC, HL7-FHIR, FDA-SaMD. Salesforce additionally lists GDPR, CCPA, POPIA, ISO27001, FedRAMP. These are vendor-stated frameworks. VektorIndex has not independently audited these claims.
Does Epic Systems or Salesforce list POPIA as a supported compliance framework?+
Salesforce lists POPIA (Protection of Personal Information Act) as a supported compliance framework per its vendor documentation. VektorIndex has not independently verified this claim. South African organisations should request the vendor's current Data Processing Agreement and confirm data residency settings before processing personal information. Epic Systems does not list POPIA as a supported compliance framework in its public documentation. Contact the vendor to confirm their position before processing South African personal information.
Which has a higher documented API rate limit — Epic Systems or Salesforce?+
Salesforce has a higher documented API rate limit at 1000 req/min versus Epic Systems at 200 req/min.
Which data hosting regions do Epic Systems and Salesforce support?+
Epic Systems lists hosting regions: US-East, US-West. Salesforce lists hosting regions: US-East, EU-West, AP-Southeast, AU-East. For data residency requirements in United States, confirm exact region configuration directly with each vendor.
Data last updated: 29 August 2026 — Sourced from official vendor documentation. Not independently audited. Report incorrect information
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